Patience and Composure

At what point does the philosophy of remaining polite towards people who consistently try your nerves need to be thrown out so that you can replace your focus where it should be?

They pester you on a consistent basis, so you do your best to remain polite towards them, even though you don't particularly like them. Then, it comes church time, and they continue to try and talk to you throughout the entire service. You're presented with a few options.

1.) Remain patient and polite with them, perhaps smile and nod and absentmindedly respond, but in reality paying them as little heed as possible and trying to focus on the message.

2.) Meet whatever they say/do with a stoic and impassive demeanor, giving no reaction to anything. Keep a hard focus on the speaker, and hope they pick up on the hint that you really don't want to listen to whatever they're trying to tell you.

3.) Break your focus, and possible that of those around you, by telling them to be quiet so you can hear; should the problem persist, do you get harsher until they get the point?

True, you might say that if the same person does this consistently, you should find a different place to sit the next time. However, in a room that's not nearly full and with a person that will follow you wherever you go even if you ignore them entirely, that doesn't work. If you never want to be around them in the first place, and they're not even the right type of person to be hanging out with anyways, but you can't seem to stay away from them due to their following you and insisting on hanging out with you, then what, pray tell, can one do?

I say, deal or die. And dying, while it would solve the problem, isn't really the best of choices.